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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
52.12
Human Site:
Y1103
Identified Species:
71.67
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
Y1103
Y
K
K
K
E
E
L
Y
L
Q
R
V
A
E
L
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
Y1103
Y
K
K
K
E
E
L
Y
L
Q
R
V
A
E
L
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
Y1102
Y
K
K
K
E
E
L
Y
L
Q
R
V
A
E
L
Dog
Lupus familis
XP_535848
1288
147094
Y1103
Y
K
K
K
E
E
L
Y
L
Q
R
V
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
Y1101
Y
K
K
K
E
D
L
Y
L
Q
R
V
A
E
L
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
F1038
L
E
S
V
R
D
K
F
Q
E
T
S
D
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
I886
R
V
G
E
L
D
K
I
T
N
E
R
E
N
F
Chicken
Gallus gallus
NP_989849
1274
145838
Y1074
Y
R
R
K
E
E
L
Y
L
K
R
V
A
E
L
Frog
Xenopus laevis
P50532
1290
146971
Y1097
Y
K
K
K
E
E
L
Y
L
Q
R
V
A
E
L
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
Y1102
F
K
K
K
E
E
L
Y
L
Q
R
V
A
E
L
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
Y1098
Y
R
K
K
E
E
L
Y
L
Q
R
V
A
Q
L
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
S1456
A
N
E
E
L
Q
K
S
L
Q
Q
K
Q
L
L
Honey Bee
Apis mellifera
XP_396862
1282
148175
Y1016
Y
K
E
K
D
A
L
Y
L
Q
R
V
T
D
V
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
Y1190
Y
V
D
K
V
K
Q
Y
N
E
Q
V
I
K
L
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
Y1100
Y
K
K
K
E
E
N
Y
L
Q
R
V
S
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
Y1054
Y
R
S
K
V
E
L
Y
N
G
R
V
D
E
L
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
V1201
D
E
L
R
E
L
D
V
E
L
I
E
S
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
0
80
100
93.3
86.6
20
60
33.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
13.3
100
100
100
100
46.6
86.6
60
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
6
0
0
0
0
0
0
53
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
6
0
6
18
6
0
0
0
0
0
12
6
0
% D
% Glu:
0
12
12
12
65
59
0
0
6
12
6
6
6
65
0
% E
% Phe:
6
0
0
0
0
0
0
6
0
0
0
0
0
0
12
% F
% Gly:
0
0
6
0
0
0
0
0
0
6
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
6
0
0
6
0
6
0
6
% I
% Lys:
0
53
53
77
0
6
18
0
0
6
0
6
0
12
0
% K
% Leu:
6
0
6
0
12
6
65
0
71
6
0
0
0
6
71
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
0
0
6
0
12
6
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
6
0
6
65
12
0
6
6
0
% Q
% Arg:
6
18
6
6
6
0
0
0
0
0
71
6
0
0
0
% R
% Ser:
0
0
12
0
0
0
0
6
0
0
0
6
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
6
0
6
0
6
0
0
% T
% Val:
0
12
0
6
12
0
0
6
0
0
0
77
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
71
0
0
0
0
0
0
77
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _